Resurfacing Scar Revision

Hyaluronic Acid Gels: A Promising Solution for Minimizing Acne Scars

Acne scars, a common aftermath of severe acne, can significantly impact an individual’s self-esteem and quality of life. However, recent advancements in dermatological treatments have introduced an effective solution: Hyaluronic Acid (HA) gels. This blog post explores the positive effects of using HA gels in minimizing acne scars, supported by findings from five peer-reviewed studies.

Understanding Hyaluronic Acid Gels

Hyaluronic Acid is a naturally occurring substance in the human body, known for its exceptional biocompatibility and low incidence of hypersensitity. Its ability to induce collagen production and improve skin hydration makes it a valuable agent in skin rejuvenation and scar treatment.

Research Highlights on HA Gels for Acne Scars

  1. Immediate and Long-Term Improvements: A study by Dierickx, Larsson, & Blomster (2018) in Dermatologic Surgery reported significant improvement in moderate-to-severe atrophic acne scars following HA gel injections, with results lasting up to 36 weeks post-treatment (Dierickx, Larsson, & Blomster, 2018).
  2. Safety and Effectiveness: Research published in Dermatologic Surgery highlighted the safety and effectiveness of HA gel treatment for acne scars, noting immediate visual improvements and well-tolerated treatments among patients (Dierickx, Larsson, & Blomster, 2018).
  3. Enhanced Facial Appearance: A study in the Journal of Drugs in Dermatology demonstrated that Restylane® Vital, a low-viscosity HA gel, significantly improved deep ice pick acne scars, offering immediate improvement and high tolerance (Shlomit et al, 2013)
  4. Combination Treatments: The Journal of Drugs in Dermatology also reported on the sequential treatment with topical retinoids and injectable HA gels, showing an improvement in the appearance of atrophic acne scars. (Shlomit et al, 2013)
  5. Collagen Stimulation: An article in Dermatologic Surgery discussed the role of HA in stimulating collagen production, contributing to long-term skin repair and scar minimization (Dierickx, Larsson, & Blomster, 2018).


Hyaluronic Acid gels have emerged as a promising solution for minimizing acne scars. Their ability to provide immediate aesthetic improvements, combined with a high safety profile and the potential for long-term skin repair, makes them a preferred choice for both practitioners and patients. As research continues to evolve, the scope of HA gel treatments in scar management is expected to expand, offering new hope to those affected by acne scars.


  1. Almukhadeb E, Binkhonain F, Alkahtani A, Alhunaif S, Altukhaim F, Alekrish K. Dermal Fillers in the Treatment of Acne Scars: A Review. Ann Dermatol. 2023 Dec;35(6):400-407. doi: 10.5021/ad.22.230. PMID: 38086353; PMCID: PMC10733075.
  2. Cunliffe WJ, Gould DJ. Prevalence of facial acne vulgaris in late adolescence and in adults. Br Med J. 1979 Apr 28;1(6171):1109-10. doi: 10.1136/bmj.1.6171.1109. PMID: 156054; PMCID: PMC1598727.
  3. Dierickx, Christine MD*; Larsson, Markus K. PhD, MSc; Blomster, Stina MSc. Effectiveness and Safety of Acne Scar Treatment With Nonanimal Stabilized Hyaluronic Acid Gel. Dermatologic Surgery 44():p S10-S18, November 2018. | DOI: 10.1097/DSS.0000000000001689
  4. Shlomit et al. Treatment of Acne Scars with Hyaluronic Acid: An Improved Approach. Journal of Drugs in Dermatology 12(7):p 121-123